Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer

steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...

s and probably also

phospholipid Phospholipids, are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typ ...

s and

ganglioside A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. ''N''-acetylneuraminic acid, NANA) linked on the sugar chain. NeuNAc, an acetylated derivative of the carbohydrate sia ...

s between cellular membranes. These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from

Thermus thermophilus ''Thermus thermophilus'' is a Gram-negative bacterium used in a range of biotechnological applications, including as a model organism for genetic manipulation, structural genomics, and systems biology. The bacterium is extremely thermophilic, w ...

. This domain is involved in binding sterols. The human sterol carrier protein 2 (

SCP2 Non-specific lipid-transfer protein also known as sterol carrier protein 2 (SCP-2) or propanoyl-CoA C-acyltransferase is a protein that in humans is encoded by the ''SCP2'' gene. Function This gene encodes two proteins: sterol carrier protein ...

) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids.

Human proteins containing this domain

HSD17B4 D-bifunctional protein (DBP), also known as peroxisomal multifunctional enzyme type 2 (MFP-2), as well as 17β-hydroxysteroid dehydrogenase type IV (17β-HSD type IV) is a protein that in humans is encoded by the ''HSD17B4'' gene. It's an alcoho ...

;

HSDL2 HSDL may refer to: *Dilling Airport *Homeland Security Digital Library The Center for Homeland Defense and Security at the Naval Postgraduate School (NPS) in Monterey, California is a school focusing on homeland security education. The Center's ...

;

STOML1 Stomatin-like protein 1 is a protein that in humans is encoded by the ''STOML1'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ...

;

References

External links

Sterol carrier proteins
in

SCOP A ( or ) was a poet as represented in Old English poetry. The scop is the Old English counterpart of the Old Norse ', with the important difference that "skald" was applied to historical persons, and scop is used, for the most part, to designa ...

SCP-2 sterol transfer family
in

Pfam Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The most recent version, Pfam 35.0, was released in November 2021 and contains 19,632 families. Uses ...

* * Peripheral membrane proteins Protein domains Protein families Water-soluble transporters {{membrane-protein-stub

Human proteins containing this domain

See also

References

External links